As the nation grapples with the strictures of Prohibition, Rosa Barclay lives on a Southern California rye farm with her volatile husband, John, who has lately found another source of income far outside the federal purview. Mother to eight children, Rosa mourns the loss of four who succumbed to the mysterious wasting disease that is now afflicting young Ana and Miguel. Two daughters born of another father are in perfect health. When an act of violence shatters Rosa's resolve to maintain her increasingly dangerous existence, she flees with the children and her precious heirloom quilts to the mesa where she last saw her beloved mother alive. As a flash flood traps them in a treacherous canyon, only one man is brave, or foolhardy, enough to come to their rescue: Lars Jorgenson, Rosa's first love and the father of her healthy daughters. Together they escape to Berkeley, where a leading specialist offers their only hope of saving Ana and Miguel. Here in northern California, they create new identities to protect themselves from Rosa's vengeful husband, the police who seek her for questioning, and the gangsters Lars reported to Prohibition agents-officers representing a department often as corrupt as the Mob itself. Ever mindful that his youthful alcoholism provoked Rosa to spurn him, Lars nevertheless supports Rosa's daring plan to stake their futures on a struggling Sonoma Valley vineyard, despite the recent hardships of local winemakers whose honest labors at viticulture have, through no fault of their own, become illegal.