Number 7, who goes by the name of Marina, has heard about John Smith, and she has a pretty good feeling that he is Number 4. Marina has been stuck with the nuns for a long time, her Cepan (Adelina) having given up on their purpose on Earth and hiding her Chest. Marina makes friends with a little girl named Ella, who said that her parents died in a car crash. Marina's life gets interesting when strangers appear in the little town of Santa Teresa, where she lives.
Meanwhile, John, Six, and Sam are on the run from the police and the FBI, who thought that they were terrorists. They train, and try to find the other Numbers. As they spend more time together, John realizes that he may have feelings for someone other than Sarah.